The presence of lupus anticoagulants (LA) in plasma is a strong risk factor for thromboembolism and fetal loss. Because of this, demand for testing for LA is increasing, but the performance of clinical laboratories in terms of its detection is still a matter of concern. This is due in part to the lack of specific tests but also to the lack of standardization and application of the diagnostic criteria. The aim of this article is to review the diagnostic criteria and the many issues that may affect test results. Copyright

Laboratory testing for lupus anticoagulants : diagnostic criteria and use of screening, mixing, and confirmatory studies / A. Tripodi. - In: SEMINARS IN THROMBOSIS AND HEMOSTASIS. - ISSN 0094-6176. - 34:4(2008 Jun), pp. 373-379.

Laboratory testing for lupus anticoagulants : diagnostic criteria and use of screening, mixing, and confirmatory studies

A. Tripodi
Primo
2008

Abstract

The presence of lupus anticoagulants (LA) in plasma is a strong risk factor for thromboembolism and fetal loss. Because of this, demand for testing for LA is increasing, but the performance of clinical laboratories in terms of its detection is still a matter of concern. This is due in part to the lack of specific tests but also to the lack of standardization and application of the diagnostic criteria. The aim of this article is to review the diagnostic criteria and the many issues that may affect test results. Copyright
Antiphospholipid syndrome; Fetal loss; Thrombophilia testing; Thrombosis
Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica
giu-2008
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/57060
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