Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease-specific treatment was established. These cases suggest that in individuals with aHUS, when skin lesions of unknown origin occur, the possibility that they are due to thrombotic microangiopathy should be considered.

Skin involvement in atypical hemolytic uremic syndrome / G. Ardissino, F. Tel, S. Testa, A.V. Marzano, R. Lazzari, S. Salardi, A. Edefonti. - In: AMERICAN JOURNAL OF KIDNEY DISEASES. - ISSN 0272-6386. - 63:4(2014), pp. 652-655. [10.1053/j.ajkd.2013.09.020]

Skin involvement in atypical hemolytic uremic syndrome

G.L. Ardissino;F. Tel;A.V. Marzano;
2014

Abstract

Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease-specific treatment was established. These cases suggest that in individuals with aHUS, when skin lesions of unknown origin occur, the possibility that they are due to thrombotic microangiopathy should be considered.
case report; eculizumab; Haemolytic uremic syndrome; plasma exchange; skin; thrombotic microangiopathy; Adult; Antibodies, Monoclonal, Humanized; Atypical Hemolytic Uremic Syndrome; Complement Factor H; Female; Hemolytic-Uremic Syndrome; Humans; Male; Plasma Exchange; Skin; Skin Diseases; Nephrology
Settore MED/35 - Malattie Cutanee e Veneree
2014
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/553856
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