The ascending fibers releasing norepinephrine and acetylcholine are highly active during wakefulness. In contrast, during rapid-eye-movement sleep, the neocortical tone is sustained mainly by acetylcholine. By comparing the different physiological features of the norepinephrine and acetylcholine systems in the light of the GANE (glutamate amplifies noradrenergic effects) model, we suggest how to interpret some functional differences between waking and rapid-eye-movement sleep.
Why we forget our dreams : acetylcholine and norepinephrine in wakefulness and REM sleep / A. Becchetti, A. Amadeo. - In: BEHAVIORAL AND BRAIN SCIENCES. - ISSN 0140-525X. - 39:(2016), pp. e202.20-e202.21. [10.1017/S0140525X15001739]
Why we forget our dreams : acetylcholine and norepinephrine in wakefulness and REM sleep
A. Amadeo
2016
Abstract
The ascending fibers releasing norepinephrine and acetylcholine are highly active during wakefulness. In contrast, during rapid-eye-movement sleep, the neocortical tone is sustained mainly by acetylcholine. By comparing the different physiological features of the norepinephrine and acetylcholine systems in the light of the GANE (glutamate amplifies noradrenergic effects) model, we suggest how to interpret some functional differences between waking and rapid-eye-movement sleep.
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