A simple synthesis enable us to obtain the progestin gestodene, in five steps and satisfatory yields from 18-methyl-estren-3,17-dione. This was accomplished through the selective protection of C-3 carbonyl group aa a cyclic ketal and the installation of a phenylsulfoxide group at the C-16 position
A simple synthesis of gestodene from 18-methyl-4-estren-3,17-dione / P. Ferraboschi, P. Grisenti, A. Onofri, P. Prestileo. - In: SYNLETT. - ISSN 0936-5214. - 2004:10(2004 Aug 09), pp. 1838-1840.
A simple synthesis of gestodene from 18-methyl-4-estren-3,17-dione
P. FerraboschiPrimo
;
2004
Abstract
A simple synthesis enable us to obtain the progestin gestodene, in five steps and satisfatory yields from 18-methyl-estren-3,17-dione. This was accomplished through the selective protection of C-3 carbonyl group aa a cyclic ketal and the installation of a phenylsulfoxide group at the C-16 position
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