Palladium-catalysed reactions of aryl iodides/vinyl triflates with 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]buta-1,3-di ynyl)-phenyl)-acetamide provide a straightforward entry into 3,3'-disubstituted-2,2'-biindolyls. Subsequent application of the procedure to homochiral aryl iodides affords the corresponding chiral 3,3'-disubstituted-2,2'-biindolyls. The methodology can also be applied to the synthesis of benzo[c]indolo[2,3-a]carbazoles. (c) 2006 Elsevier Ltd. All rights reserved.
Synthesis of 3,3'-disubstituted-2,2'-biindolyls through sequential palladium-catalysed reactions of 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]-buta-1,3-d iynyl)-phenyl)-acetamide with organic halides/triflates / G. Abbiati, A. Arcadi, E. M. Beccalli, G. Bianchi, F. Marinelli, E. Rossi. - In: TETRAHEDRON. - ISSN 0040-4020. - 62:13(2006 Mar 17), pp. 3033-3039.
Synthesis of 3,3'-disubstituted-2,2'-biindolyls through sequential palladium-catalysed reactions of 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]-buta-1,3-d iynyl)-phenyl)-acetamide with organic halides/triflates
G. AbbiatiPrimo
;E. M. Beccalli;E. RossiUltimo
2006
Abstract
Palladium-catalysed reactions of aryl iodides/vinyl triflates with 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]buta-1,3-di ynyl)-phenyl)-acetamide provide a straightforward entry into 3,3'-disubstituted-2,2'-biindolyls. Subsequent application of the procedure to homochiral aryl iodides affords the corresponding chiral 3,3'-disubstituted-2,2'-biindolyls. The methodology can also be applied to the synthesis of benzo[c]indolo[2,3-a]carbazoles. (c) 2006 Elsevier Ltd. All rights reserved.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.