Hormone replacement therapy in menopause has been associated with a moderate increase in ovarian cancer risk. Data on combined estrogen-progestin therapy, based on one randomized trial, two cohort and four case-control studies, do not provide definite evidence of an association between combined hormone replacement therapy and ovarian cancer. These data do not suggest, however, substantial differences between the effect of estrogen only or unspecified hormone replacement therapy and combined hormone replacement therapy on ovarian cancer risk.
Estrogen-progestogen replacement therapy and ovarian cancer : an update / C. La Vecchia. - In: EUROPEAN JOURNAL OF CANCER PREVENTION. - ISSN 0959-8278. - 15:6(2006 Dec), pp. 490-492. [10.1097/01.cej.0000205026.14515.de]
Estrogen-progestogen replacement therapy and ovarian cancer : an update
C. La VecchiaPrimo
2006
Abstract
Hormone replacement therapy in menopause has been associated with a moderate increase in ovarian cancer risk. Data on combined estrogen-progestin therapy, based on one randomized trial, two cohort and four case-control studies, do not provide definite evidence of an association between combined hormone replacement therapy and ovarian cancer. These data do not suggest, however, substantial differences between the effect of estrogen only or unspecified hormone replacement therapy and combined hormone replacement therapy on ovarian cancer risk.Pubblicazioni consigliate
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