A description of huntingtons disease and the gene which is responsible for it is presented. Huntingtons disease, which cripples and causes dementia is a genetic disease that results from a mutation in a gene called huntingtin found on chromosome 4. Mutant hutingtin appears to be toxic to key nerve cells in the brain and lacks the ability to turn on a necessary growth factor gene.

The Enigma of Huntington’s Disease / E. Cattaneo, D. Rigamonti, C. Zuccato. - In: SCIENTIFIC AMERICAN. - ISSN 0036-8733. - 287:6(2002), pp. 92-97.

The Enigma of Huntington’s Disease

E. Cattaneo
Primo
;
C. Zuccato
Ultimo
2002

Abstract

A description of huntingtons disease and the gene which is responsible for it is presented. Huntingtons disease, which cripples and causes dementia is a genetic disease that results from a mutation in a gene called huntingtin found on chromosome 4. Mutant hutingtin appears to be toxic to key nerve cells in the brain and lacks the ability to turn on a necessary growth factor gene.
Settore BIO/14 - Farmacologia
2002
http://www.scientificamerican.com/article.cfm?id=the-enigma--of-huntington
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/198317
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