We report two childhood cases of monilethrix treated with L-cystine orally at a dose of 500 mg twice daily for 3 months. At the end of the treatment period clinical and ultrastructural improvements of the hair were recorded by scanning electron microscopy. An increase in hair length and a regularization of the cuticular architecture were the most significant results. Since there is no universally accepted treatment for monilethrix, several therapeutic approaches have been proposed. We suggest L-cystine as a possible choice on the basis of its known positive role during the keratinization process and its safety for treatment lasting several months.
Ultrastructural and clinical improvement in monilethrix treated with L-cystine / S.Menni,M.Barbareschi ,I.Brauner , M. De Souza Viganò,. - In: THE JOURNAL OF DERMATOLOGICAL TREATMENT. - ISSN 0954-6634. - 4:3(1993), pp. 149-151. [10.3109/09546639309080555]
Ultrastructural and clinical improvement in monilethrix treated with L-cystine
S. MenniPrimo
;M. BarbareschiSecondo
;
1993
Abstract
We report two childhood cases of monilethrix treated with L-cystine orally at a dose of 500 mg twice daily for 3 months. At the end of the treatment period clinical and ultrastructural improvements of the hair were recorded by scanning electron microscopy. An increase in hair length and a regularization of the cuticular architecture were the most significant results. Since there is no universally accepted treatment for monilethrix, several therapeutic approaches have been proposed. We suggest L-cystine as a possible choice on the basis of its known positive role during the keratinization process and its safety for treatment lasting several months.Pubblicazioni consigliate
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