An elderly man with relapsing myasthenia gravis was found to have hypergammaglobulinaemia, a monoclonal peak of gamma mobility and paraproteinaemia IgG, type K. Bence-Jones proteinuria, type K was present. This is the fourth report of myasthenia gravis associated with a monoclonal gammopathy. Myasthenia gravis is considered to be an autoimmune disease. Recent findings implicate a dysfunction of cellular immunity in the pathogenesis of both immunoproliferative and autoimmune disease. We suggest that the association of myasthenia gravis and monoclonal gammopathy in our patient might have stemmed from a disorder of T lymphocyte function.
Myasthenia gravis with a monoclonal gammopathy--report of a case / M. Galli, G. Landi, D. L. Restelli, G. Scarlato. - In: JOURNAL OF THE NEUROLOGICAL SCIENCES. - ISSN 0022-510X. - 45:1(1980 Feb), pp. 103-108.
Myasthenia gravis with a monoclonal gammopathy--report of a case
M. GalliPrimo
;
1980
Abstract
An elderly man with relapsing myasthenia gravis was found to have hypergammaglobulinaemia, a monoclonal peak of gamma mobility and paraproteinaemia IgG, type K. Bence-Jones proteinuria, type K was present. This is the fourth report of myasthenia gravis associated with a monoclonal gammopathy. Myasthenia gravis is considered to be an autoimmune disease. Recent findings implicate a dysfunction of cellular immunity in the pathogenesis of both immunoproliferative and autoimmune disease. We suggest that the association of myasthenia gravis and monoclonal gammopathy in our patient might have stemmed from a disorder of T lymphocyte function.Pubblicazioni consigliate
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