Ring opening reactions of the spiro-β-lactam 5-benzoyl-3-phenyl-2-phenylsulfonyl-7-thia-2,5-diazaspiro[3.4]octan-1-one (1a) under hydrolytic, reductive and alkylating reaction conditions are reported. There is evidence for the influence of the spiro structure on azetidinone ring reactivity, which is also affected by the presence of the N-phenylsulfonyl group.
Studies on ring opening reactions of N-phenylsulfonyl substituted spiro-beta-lactams / P. Dalla Croce, C. La Rosa. - In: HETEROCYCLES. - ISSN 0385-5414. - 53:12(2000), pp. 2653-2660.
Studies on ring opening reactions of N-phenylsulfonyl substituted spiro-beta-lactams
P. Dalla CrocePrimo
;C. La RosaUltimo
2000
Abstract
Ring opening reactions of the spiro-β-lactam 5-benzoyl-3-phenyl-2-phenylsulfonyl-7-thia-2,5-diazaspiro[3.4]octan-1-one (1a) under hydrolytic, reductive and alkylating reaction conditions are reported. There is evidence for the influence of the spiro structure on azetidinone ring reactivity, which is also affected by the presence of the N-phenylsulfonyl group.
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