A mass fragmentographic method for the measurement of 3 methoxytyramine, a metabolite of dopamine formed after its neuronal release, is described. This method allows the assay of this dopamine metabolite in the picogram range, thus utilizing only a few miligrams of brain areas containing dopaminergic neurons. Moreover, the method is simple and possesses the high specificity intrinsic to mass fragmentography.
A mass fragmentographic assay of 3-methoxytyramine in rat brain / C.L. Galli, F. Cattabeni, F.P. Spano, T. Eros, S. Algeri, A.M. Di Giulio, A. Groppetti. - In: JOURNAL OF NEUROCHEMISTRY. - ISSN 0022-3042. - 27:3(1976), pp. 795-798.
A mass fragmentographic assay of 3-methoxytyramine in rat brain
C.L. Galli;F. Cattabeni;A.M. Di Giulio;
1976
Abstract
A mass fragmentographic method for the measurement of 3 methoxytyramine, a metabolite of dopamine formed after its neuronal release, is described. This method allows the assay of this dopamine metabolite in the picogram range, thus utilizing only a few miligrams of brain areas containing dopaminergic neurons. Moreover, the method is simple and possesses the high specificity intrinsic to mass fragmentography.
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