A new synthesis of α-carbolines was developed starting from the easily accessible 3-substituted indol-2(3H)-one derivatives 2 and enamines 3. The intermediates 4 afforded the α-carbolines 5 and 6 by thermal cyclization with ammonium acetate in glacial acetic acid by way of pyridine ring formation.
An alternative approach to the synthesis of functionalized pyrido[2,3-b]indoles / E.M. Beccalli, F. Clerici, A. Marchesini. - In: TETRAHEDRON. - ISSN 0040-4020. - 57:22(2001), pp. 4787-4792. [10.1016/S0040-4020(01)00404-5]
An alternative approach to the synthesis of functionalized pyrido[2,3-b]indoles
E.M. BeccalliPrimo
;F. ClericiSecondo
;A. MarchesiniUltimo
2001
Abstract
A new synthesis of α-carbolines was developed starting from the easily accessible 3-substituted indol-2(3H)-one derivatives 2 and enamines 3. The intermediates 4 afforded the α-carbolines 5 and 6 by thermal cyclization with ammonium acetate in glacial acetic acid by way of pyridine ring formation.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
