Method for determining the changes induced by the skin in heterophase matrices characterized in that: - a thin film of a formulation which is capable of transferring specific elements through the skin and changing its permeability are applied topically to the affected part of the body, - a homogeneous layer of the heterophase matrix under test is then applied to the skin covered with the said thin film, - immediately after this application a portion of the homogeneous layer of the heterophase matrix is taken for use as a reference, - the homogeneous layer of the heterophase matrix is restored and after a predetermined period of time a second portion of homogeneous layer is removed from the same area of the skin by the same means, and - the two samples are subjected to a flow test to determine changes in thixotropy within the scope of the entire mud treatment cycle.

Method for determining changes induced by the skin on heterophase matrices applied to it and formulation to implement the method / A. Bettero, A. Gazzaniga.

Method for determining changes induced by the skin on heterophase matrices applied to it and formulation to implement the method

A. Gazzaniga
Ultimo
1995

Abstract

Method for determining the changes induced by the skin in heterophase matrices characterized in that: - a thin film of a formulation which is capable of transferring specific elements through the skin and changing its permeability are applied topically to the affected part of the body, - a homogeneous layer of the heterophase matrix under test is then applied to the skin covered with the said thin film, - immediately after this application a portion of the homogeneous layer of the heterophase matrix is taken for use as a reference, - the homogeneous layer of the heterophase matrix is restored and after a predetermined period of time a second portion of homogeneous layer is removed from the same area of the skin by the same means, and - the two samples are subjected to a flow test to determine changes in thixotropy within the scope of the entire mud treatment cycle.
RICERCHE E INNOVAZIONI & TECNO
IT1249509
23-feb-1995
Settore CHIM/09 - Farmaceutico Tecnologico Applicativo
Method for determining changes induced by the skin on heterophase matrices applied to it and formulation to implement the method / A. Bettero, A. Gazzaniga.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/184162
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