We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.
Ear lobe bilateral necrosis by levamisole induced occlusive vasculitis in a pediatric patient / S. Menni, G. Pistritto, R. Gianotti, L. Ghio, A. Edefonti. - In: PEDIATRIC DERMATOLOGY. - ISSN 0736-8046. - 14:6(1997 Nov), pp. 477-479.
Ear lobe bilateral necrosis by levamisole induced occlusive vasculitis in a pediatric patient
S. Menni;R. Gianotti;
1997
Abstract
We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.
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