The EMG of costal and crural parts of diaphragm has been evaluated in 6 anaesthetized (Thiopental-sodium mg 15/kg i.v.) and tracheostomized newborn pigs. The EMG has been evaluated in control conditions and after PGF2alpha administration (mg 0.15-0.20/kg i.v.) The experiments were performed also after bilateral vagotomy. Our results showed an inhibitory vagal mechanism regulating the diaphragmatic EMG. This mechanism may be modified by PGF2alpha that induces a postinspiratory diaphragmatic activity. PGF2alpha after vagotomy did not cause significant changes. One could conclude that a reflex vagal mechanism is present and the diaphragmatic response to PGF2alpha is vagal dependent.
Effetti della PGF2alfa sul diaframma nel maiale neonato / M. Albertini, M.G. Clement, M. Dimori - In: Atti della Società Italiana delle Scienze Veterinarie[s.l] : Società Italiana Scienze Veterinarie, 1991 Sep. - pp. 367-371 (( Intervento presentato al 45. convegno Convegno SISVet tenutosi a Altavilla Milicia nel 1991.
Effetti della PGF2alfa sul diaframma nel maiale neonato
M. AlbertiniPrimo
;M.G. ClementSecondo
;
1991
Abstract
The EMG of costal and crural parts of diaphragm has been evaluated in 6 anaesthetized (Thiopental-sodium mg 15/kg i.v.) and tracheostomized newborn pigs. The EMG has been evaluated in control conditions and after PGF2alpha administration (mg 0.15-0.20/kg i.v.) The experiments were performed also after bilateral vagotomy. Our results showed an inhibitory vagal mechanism regulating the diaphragmatic EMG. This mechanism may be modified by PGF2alpha that induces a postinspiratory diaphragmatic activity. PGF2alpha after vagotomy did not cause significant changes. One could conclude that a reflex vagal mechanism is present and the diaphragmatic response to PGF2alpha is vagal dependent.
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