Various amounts of carbon dioxide were removed through an extracorporeal membrane lung in spontaneously breathing lambs. The decrease in alveolar ventilation was proportional to the fraction of total carbon dioxide removed by the membrane lung. When extracorporeal CO2 removal approximated CO2 production (VCO2), alveolar ventilation almost ceased. Pulmonary ventilation can be controlled by extracorporeal carbon dioxide removal.
Control of breathing using an extracorporeal membrane lung / T. Kolobow, L. Gattinoni, T.A. Tomlinson, J.E. Pierce. - In: ANESTHESIOLOGY. - ISSN 0003-3022. - 46:2(1977 Feb), pp. 138-141. [10.1097/00000542-197702000-00012]
Control of breathing using an extracorporeal membrane lung
L. GattinoniSecondo
;
1977
Abstract
Various amounts of carbon dioxide were removed through an extracorporeal membrane lung in spontaneously breathing lambs. The decrease in alveolar ventilation was proportional to the fraction of total carbon dioxide removed by the membrane lung. When extracorporeal CO2 removal approximated CO2 production (VCO2), alveolar ventilation almost ceased. Pulmonary ventilation can be controlled by extracorporeal carbon dioxide removal.
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