In 14 anaesthetized (Thiopental-sodium mg 15/kg iv) and tracheostomized pigs were evaluated the respiratory and circulatory responses evocated by PAF (25-50 ng/kg iv). PAF caused an increase in pulmonary arterial pressure, systemic hypotension, decrease in compliance (Crs) and increase in respiratory resistances. The decrease in Crs modified the VT/TI relationship showin the vagal activity on respiratory centres. Therefore our results show the PAF, acting on vagal afferences, modifies the bulbo-pontine activity.
Modificazioni del ritmo bulbo-pontino indotte da platelet activating factor (PAF) / M. Dimori, M. Albertini, M.G. Clement. - In: ATTI DELLA SOCIETA' ITALIANA DELLE SCIENZE VETERINARIE. - ISSN 1721-1980. - 45:(1991), pp. 373-377. ((Intervento presentato al 45. convegno Convegno nazionale SISVet tenutosi a Palermo nel 1991.
Modificazioni del ritmo bulbo-pontino indotte da platelet activating factor (PAF)
M. AlbertiniSecondo
;M.G. ClementUltimo
1991
Abstract
In 14 anaesthetized (Thiopental-sodium mg 15/kg iv) and tracheostomized pigs were evaluated the respiratory and circulatory responses evocated by PAF (25-50 ng/kg iv). PAF caused an increase in pulmonary arterial pressure, systemic hypotension, decrease in compliance (Crs) and increase in respiratory resistances. The decrease in Crs modified the VT/TI relationship showin the vagal activity on respiratory centres. Therefore our results show the PAF, acting on vagal afferences, modifies the bulbo-pontine activity.Pubblicazioni consigliate
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