Rac1 is signal transducer involved in several events related to both cardiovascular disease and cancer.We will discuss the application of different computational methods for the identification and design of new inhibitors of Rac1, as well as their synthesis and pharmacological evaluation
Design Of New Rac1 Inhibitors Through Computational Approaches / A. Contini, S. Stragliotto, N. Ferri. ((Intervento presentato al convegno Computationally Driven Drug Discovery Meeting CDDD Meeting tenutosi a L'Aquila nel 2011.
Design Of New Rac1 Inhibitors Through Computational Approaches
A. ContiniPrimo
;S. StragliottoSecondo
;N. FerriUltimo
2011
Abstract
Rac1 is signal transducer involved in several events related to both cardiovascular disease and cancer.We will discuss the application of different computational methods for the identification and design of new inhibitors of Rac1, as well as their synthesis and pharmacological evaluation
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