Symbiotic bacteria of the genus have been proposed as tools for control of mosquito-borne diseases, specifically malaria. However, safety issues are a major concern for paratransgenesis strategies. The aim of this study is to investigate, with immunofluorescence assays and quantitative PCR experiments, whether spp. is circulating among humans. All human sera and whole blood samples analyzed were negative for spp., thus suggesting that this organism could be utilized, in the future, as a malaria control tool.
Do mosquito-associated bacteria of the genus Asaia circulate in humans? / S. Epis, P. Gaibani, U. Ulissi, B. Chouaia, I. Ricci, C. Damiani, V. Sambri, F. Castelli, F. Buelli, D. Daffonchio, C. Bandi, G. Favia. - In: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. - ISSN 0934-9723. - 31:6(2012 Jun), pp. 1137-1140. [10.1007/s10096-011-1419-3]
Do mosquito-associated bacteria of the genus Asaia circulate in humans?
S. Epis;B. Chouaia;D. Daffonchio;C. Bandi;
2012
Abstract
Symbiotic bacteria of the genus have been proposed as tools for control of mosquito-borne diseases, specifically malaria. However, safety issues are a major concern for paratransgenesis strategies. The aim of this study is to investigate, with immunofluorescence assays and quantitative PCR experiments, whether spp. is circulating among humans. All human sera and whole blood samples analyzed were negative for spp., thus suggesting that this organism could be utilized, in the future, as a malaria control tool.
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