The discovery of opioid receptor expression on immune cells has originated a large research activity on the possible modulation by opioid drugs of immune system responses. In this chapter we describe an easy methodology useful to obtain information about the potential immunomodulatory activity of opioid drugs. An in vivo treatment schedule is used, and macrophages are studied for their ability to release different cytokines.
Evaluation of Murine Macrophage Cytokine Production After In Vivo Morphine Treatment / S. Franchi, M. Castelli, S. Moretti, A.E. Panerai, P.G. Sacerdote (METHODS IN MOLECULAR BIOLOGY). - In: Opioid Receptors : Methods and Protocols / [a cura di] S.M. Spampinato. - [s.l] : Springer, 2021. - ISBN 9781071608838. - pp. 199-207 [10.1007/978-1-0716-0884-5_18]
Evaluation of Murine Macrophage Cytokine Production After In Vivo Morphine Treatment
S. Franchi;M. Castelli;A.E. Panerai;P.G. Sacerdote
2021
Abstract
The discovery of opioid receptor expression on immune cells has originated a large research activity on the possible modulation by opioid drugs of immune system responses. In this chapter we describe an easy methodology useful to obtain information about the potential immunomodulatory activity of opioid drugs. An in vivo treatment schedule is used, and macrophages are studied for their ability to release different cytokines.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Franchi2021_Protocol_EvaluationOfMurineMacrophageCy.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
261.3 kB
Formato
Adobe PDF
|
261.3 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
