Honey contaminations could derive from intensive agriculture and industrial activities, but also from beekeeper treatments. In EU no MRLs for antibiotics in honey are set, only a minimum required performance limit for chloramphenicol of 0.3 μg kg−1 is recommended. Screening tests are available, characterised by their rapidity and simple use. Due to their high rate of false positives and the need to meet zero tolerance levels for antibiotics, their presence in samples was investigated using a liquid chromatography High Resolution Mass Spectrometry (LC-HRMS) multiclass antibiotic residue method, comparing the results with those of previous screening tests. The confirmatory method showed good sensitivity: CCα and CCβ ranging from 0.03 to 4.80 ng g−1 and from 0.12 to 5.56 ng g−1, respectively. Ninety-eight honey samples from different geographical areas, analysed by two screening tests, showed a high percentage of false positives. This is fundamental to guarantee honey safety, especially, for organic production.

Determination of antibiotic residues in honey in relation to different potential sources and relevance for food inspection / E. Bonerba, S. Panseri, F. Arioli, M. Nobile, V. Terio, F. Di Cesare, G. Tantillo, L. Maria Chiesa. - In: FOOD CHEMISTRY. - ISSN 0308-8146. - 334(2021 Jan 01). [10.1016/j.foodchem.2020.127575]

Determination of antibiotic residues in honey in relation to different potential sources and relevance for food inspection

S. Panseri
Secondo
;
F. Arioli;M. Nobile
;
F. Di Cesare;L. Maria Chiesa
Ultimo
2021

Abstract

Honey contaminations could derive from intensive agriculture and industrial activities, but also from beekeeper treatments. In EU no MRLs for antibiotics in honey are set, only a minimum required performance limit for chloramphenicol of 0.3 μg kg−1 is recommended. Screening tests are available, characterised by their rapidity and simple use. Due to their high rate of false positives and the need to meet zero tolerance levels for antibiotics, their presence in samples was investigated using a liquid chromatography High Resolution Mass Spectrometry (LC-HRMS) multiclass antibiotic residue method, comparing the results with those of previous screening tests. The confirmatory method showed good sensitivity: CCα and CCβ ranging from 0.03 to 4.80 ng g−1 and from 0.12 to 5.56 ng g−1, respectively. Ninety-eight honey samples from different geographical areas, analysed by two screening tests, showed a high percentage of false positives. This is fundamental to guarantee honey safety, especially, for organic production.
Honey; Antibiotics; High Resolution Mass Spectrometry; LC-HRMS; Screening tests; Food inspection;
Settore VET/04 - Ispezione degli Alimenti di Origine Animale
Settore VET/07 - Farmacologia e Tossicologia Veterinaria
1-gen-2021
18-lug-2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/754396
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