The authors report the preliminary results of a prospective study in 30 patients with gastro-oesophageal reflux disease. The aim was to assess the efficacy of an-original device designed to augment the lower oesophageal sphincter barrier using magnetic force. The device was placed laparoscopically around the oesophagogastric junction, at the level of the z line identified by intraoperative endoscopy. Transient dysphagia not requiring any treatment was recorded in 45% of patients. At 3 months postoperatively, the GORD-HRQL score was fond to be significantly decreased from 24.4 to 2.2 (p < 0.001) and the DeMeester score was normalised in 80% of patients. At one year follow-up, 100% of patients were off proton pump inhibitors, and 70% of them had a normal DeMeester score. All patients preserved the ability to belch.
Sfintere esofageo magnetico nel trattamento della malattia da reflusso gastroesofageo: risultati di uno studio prospettico / M. Nencioni, E. Asti, G. Saino, D. Bona, S. Pallotta, L. Laface, L. Bonavina. - In: CHIRURGIA ITALIANA. - ISSN 0009-4773. - 61:2(2009), pp. 187-192.
Sfintere esofageo magnetico nel trattamento della malattia da reflusso gastroesofageo: risultati di uno studio prospettico
M. NencioniPrimo
;E. AstiSecondo
;G. Saino;D. Bona;S. Pallotta;L. Laface;L. BonavinaUltimo
2009
Abstract
The authors report the preliminary results of a prospective study in 30 patients with gastro-oesophageal reflux disease. The aim was to assess the efficacy of an-original device designed to augment the lower oesophageal sphincter barrier using magnetic force. The device was placed laparoscopically around the oesophagogastric junction, at the level of the z line identified by intraoperative endoscopy. Transient dysphagia not requiring any treatment was recorded in 45% of patients. At 3 months postoperatively, the GORD-HRQL score was fond to be significantly decreased from 24.4 to 2.2 (p < 0.001) and the DeMeester score was normalised in 80% of patients. At one year follow-up, 100% of patients were off proton pump inhibitors, and 70% of them had a normal DeMeester score. All patients preserved the ability to belch.File | Dimensione | Formato | |
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