The present invention provides nitric oxide releasing hyaluronic acid derivatives of formula (I) in which the carboxylic groups of the hyaluronic acid are partially esterified with a group capable to release nitric oxide: (I) The hyaluronic acid derivatives of the invention are able to release nitric oxide (NO) and they can be advantageously used in ophthalmology.

Nitric oxide releasing hyaluronic esters / N. Almirante, L. Storoni, S. Romeo.

Nitric oxide releasing hyaluronic esters

S. Romeo
Ultimo
2019

Abstract

The present invention provides nitric oxide releasing hyaluronic acid derivatives of formula (I) in which the carboxylic groups of the hyaluronic acid are partially esterified with a group capable to release nitric oxide: (I) The hyaluronic acid derivatives of the invention are able to release nitric oxide (NO) and they can be advantageously used in ophthalmology.
Nicox S.A.
WO 2019/121488 A1
PCT/EP2018/085161
EP17209341
27-giu-2019
La présente invention concerne des dérivés d'acide hyaluronique libérant de l'oxyde nitrique de formule (I) dans laquelle les groupes carboxyliques de l'acide hyaluronique sont partiellement estérifiés avec un groupe capable de libérer de l'oxyde nitrique : (I) Les dérivés d'acide hyaluronique de l'invention sont aptes à libérer de l'oxyde nitrique (ON) et ils peuvent être avantageusement utilisés en ophtalmologie.
Settore CHIM/08 - Chimica Farmaceutica
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2019121488
Nitric oxide releasing hyaluronic esters / N. Almirante, L. Storoni, S. Romeo.
File in questo prodotto:
File Dimensione Formato  
WO2019121488A1.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 725.24 kB
Formato Adobe PDF
725.24 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/654499
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact