Arterial injury with subsequent remodelling and predisposition to arterial stenosis and/or dilation are the hallmarks of Takayasu arteritis. The degree of arterial damage closely aligns with prognosis and therefore its prevention is the predominant aim of therapy. Non-invasive imaging has greatly improved our ability to identify the extent and severity of disease and to monitor its progress. However, many questions remain concerning the optimal use of individual modalities at different stages of disease. Imaging methods for the quantification of arterial damage are lacking. Likewise, no single technique can accurately determine disease activity within the arterial wall or distinguish inflammatory and non-inflammatory disease progression. The aim of this review is to outline current imaging strategies in Takayasu arteritis, their individual roles in diagnosis and disease monitoring and potential future advances.

Application of imaging techniques for Takayasu arteritis / E. Tombetti, J. Mason. - In: LA PRESSE MÉDICALE. - ISSN 0755-4982. - 46:7-8(2017), pp. e215-e223. [10.1016/j.lpm.2017.03.022]

Application of imaging techniques for Takayasu arteritis

E. Tombetti
Primo
;
2017

Abstract

Arterial injury with subsequent remodelling and predisposition to arterial stenosis and/or dilation are the hallmarks of Takayasu arteritis. The degree of arterial damage closely aligns with prognosis and therefore its prevention is the predominant aim of therapy. Non-invasive imaging has greatly improved our ability to identify the extent and severity of disease and to monitor its progress. However, many questions remain concerning the optimal use of individual modalities at different stages of disease. Imaging methods for the quantification of arterial damage are lacking. Likewise, no single technique can accurately determine disease activity within the arterial wall or distinguish inflammatory and non-inflammatory disease progression. The aim of this review is to outline current imaging strategies in Takayasu arteritis, their individual roles in diagnosis and disease monitoring and potential future advances.
Large-vessel vasculitis; contrast-enhanced ultrasound; giant-cell arteritis; disease-activity; CT angiography; F-18-FDG pet; MR-angiography; computed-tomography; emission-tomography; follow-up
Settore MED/09 - Medicina Interna
Settore MED/16 - Reumatologia
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Settore MED/36 - Diagnostica per Immagini e Radioterapia
2017
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/593034
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