With the goal to indentifying the emerging concepts universal in tumor development from cancer stem cells, we have generated a dog cancer stem cell model system. Insight into the hierarchical organization of canine tumors as abnormal tissues that originates from, and are maintained by cancer sterm cells, should provide a mammalian tumor model system more similar to human than the rodent system.
Characterization of canine mammary tumor initiating cells with stem cell potential / C. Cocola, P. Anastasi, S. Astigiano, S. Sanzone, N. Cellamare, E. Piscitelli, L. Vilardo, E. Sala, G. Bertoli, M. Beccaglia, M.C. Veronesi, O. Barbieri, R. Reinbold, G.C. Luvoni, I. Zucchi - In: 6. International Symposium on Canine and Feline Reproduction & 6. Biennial EVSSAR Congress : "Reproductive biology and medicine of domestic and exotic carnivores" ... : abstracts / [a cura di] G. England, P. Concannon, S. Schäfer-Somi. - [S.l.] : [s.n.], 2008. - pp. 62-62 (( Intervento presentato al 6. convegno International Symposium on Canine and Feline Reproduction tenutosi a Vienna nel 2008.
Characterization of canine mammary tumor initiating cells with stem cell potential
M. Beccaglia;M.C. Veronesi;G.C. LuvoniPenultimo
;
2008
Abstract
With the goal to indentifying the emerging concepts universal in tumor development from cancer stem cells, we have generated a dog cancer stem cell model system. Insight into the hierarchical organization of canine tumors as abnormal tissues that originates from, and are maintained by cancer sterm cells, should provide a mammalian tumor model system more similar to human than the rodent system.
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