The aim of this work is to evaluate the development of X.l. in modified gravity conditions. The simulation of hyper and microgravity was performed utilizing: an hyperfuge, a Clinostat and later on a Random Positioning Machine (RPM, 3d Clinostat). The effect of hypergravity on embryos is significantly higher than that of microgravity; the exposure of embryos to 3xg for 3 days before and after hatch causes an activation of HSP-60 and HSP-70. Embryos exposed to 3xg during the first 3 days of development are very sensitive and show a retard of development, with a lower content of DNA, neutral glycolipids and gangliosides compared to controls.
Effects of microgravity and hypergravity on early development stages of Xeonopus laevis / A.M. Rizzo, F. Rossi, A. Guerra, P. Pippia, M.A. Meloni, B. Berra. - In: JOURNAL OF GRAVITATIONAL PHYSIOLOGY. - ISSN 1077-9248. - 9:1(2002), pp. P207-P208.
Effects of microgravity and hypergravity on early development stages of Xeonopus laevis.
A.M. RizzoPrimo
;F. RossiSecondo
;B. BerraUltimo
2002
Abstract
The aim of this work is to evaluate the development of X.l. in modified gravity conditions. The simulation of hyper and microgravity was performed utilizing: an hyperfuge, a Clinostat and later on a Random Positioning Machine (RPM, 3d Clinostat). The effect of hypergravity on embryos is significantly higher than that of microgravity; the exposure of embryos to 3xg for 3 days before and after hatch causes an activation of HSP-60 and HSP-70. Embryos exposed to 3xg during the first 3 days of development are very sensitive and show a retard of development, with a lower content of DNA, neutral glycolipids and gangliosides compared to controls.
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