Objective: We conducted a systematic review in order to: i. summarize the relationship between low birth weight, catch-up-growth and the metabolic syndrome, from publications during the past 10 years; and ii. study the potential role of an alternative nurtritional approach to side effects of catch-up-growth. Methods: We reviewed all papers published in the past ten years assessing the possible association between low birth weight, cathch-up-growth and the occurrence of some components of the metabolic syndrome, including insulin resistance, type 2 diabetes, dyslipidemia and non-alcoholic fatty liver disease. Results: We found 57 studies which described the relationship between metabolic syndrome associated features and low birth weight and catch-up-growth. The majority of the studies in children, adolescents and adults born small for gestational age (SGA) suggested that insulin resistance could represent the prelude to other metabolic disorders. Conclusions: Both low birth weight and catch-up-growth seem to correlate with some aspects of a later metabolic syndrome.

Low birth weight and catch-up-growth associated with metabolic syndrome: a ten-year systematic review / V. Nobili, A. Alisi, N. Panera, C. Agostoni. - In: PEDIATRIC ENDOCRINOLOGY REVIEW. - ISSN 1565-4753. - 6:2(2008), pp. 241-247.

Low birth weight and catch-up-growth associated with metabolic syndrome: a ten-year systematic review

C. Agostoni
Ultimo
2008

Abstract

Objective: We conducted a systematic review in order to: i. summarize the relationship between low birth weight, catch-up-growth and the metabolic syndrome, from publications during the past 10 years; and ii. study the potential role of an alternative nurtritional approach to side effects of catch-up-growth. Methods: We reviewed all papers published in the past ten years assessing the possible association between low birth weight, cathch-up-growth and the occurrence of some components of the metabolic syndrome, including insulin resistance, type 2 diabetes, dyslipidemia and non-alcoholic fatty liver disease. Results: We found 57 studies which described the relationship between metabolic syndrome associated features and low birth weight and catch-up-growth. The majority of the studies in children, adolescents and adults born small for gestational age (SGA) suggested that insulin resistance could represent the prelude to other metabolic disorders. Conclusions: Both low birth weight and catch-up-growth seem to correlate with some aspects of a later metabolic syndrome.
Settore MED/38 - Pediatria Generale e Specialistica
2008
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/51160
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