Concomitant use of a fibrate and a statin may offer a therapeutic advantage to patients with dyslipidemia, especially in patients whose low-density lipoprotein cholesterol is controlled by statins but whose high-density lipoprotein cholesterol or triglycerides, or both, are not within goal. However, concern about drug-drug interactions may preclude optimal use of combination statin-fibrate therapy. This article reviews the pharmacokinetics between statins and fibrates, addressing risks associated with drug-drug interactions and combination therapy. (copyright) 2005 Elsevier Inc. All rights reserved.
Pharmacokinetic interactions between statins and fibrates / A. Corsini, S. Bellosta, M.H. Davidson. - In: THE AMERICAN JOURNAL OF CARDIOLOGY. - ISSN 0002-9149. - 96:9 SUPPL. 1(2005), pp. 44K-49K.
Pharmacokinetic interactions between statins and fibrates
A. CorsiniPrimo
;S. BellostaSecondo
;
2005
Abstract
Concomitant use of a fibrate and a statin may offer a therapeutic advantage to patients with dyslipidemia, especially in patients whose low-density lipoprotein cholesterol is controlled by statins but whose high-density lipoprotein cholesterol or triglycerides, or both, are not within goal. However, concern about drug-drug interactions may preclude optimal use of combination statin-fibrate therapy. This article reviews the pharmacokinetics between statins and fibrates, addressing risks associated with drug-drug interactions and combination therapy. (copyright) 2005 Elsevier Inc. All rights reserved.File | Dimensione | Formato | |
---|---|---|---|
2005 Am J Cardiol Pharmacokinetic interactions.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
163.78 kB
Formato
Adobe PDF
|
163.78 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.