Background: Controversy prevails regarding the existence of a correlation between the severity of coronary artery disease (CAD) and the extent and distribution of obesity. Purpose: To assess the correlation between total fat, truncal fat (TF), and lean mass, obtained with dual-energy X-ray absorptiometry (DEXA) and standard anthropomorphic indices (body mass index, waist circumference, waist-to-hip ratio) and to verify whether DEXA indices can predict the extent and severity of CAD. Materials and methods: Fifty-eight patients (19 females) consecutively referred for coronary angiography underwent physical examination and DEXA assessment of body composition. Results: Of the 58 patients enrolled, 22 were overweight and 13 were obese. Significant CAD was found in 39 (67%) patients. DEXA-derived total mass and fat mass enabled us to distinguish overweight from obese patients (P < 0.005), whereas just TF mass correlated with the number of diseased vessels after adjusting for body mass index, sex, age, and smoking habit (odds ratio, 8.68; 95% confidence interval: 1.02-74.10). Conclusion: TF determined by DEXA is independently related with CAD extension.

Truncal fat determined by dual-energy X-ray absorptiometry is an independent predictor of coronary artery disease extension / A. Bestetti, D. Castini, R. Bigi, C. Maioli, F. Lombardi, D. Gregori, G. Cornalba. - In: EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION. - ISSN 1741-8267. - 15:4(2008 Aug), pp. 428-433.

Truncal fat determined by dual-energy X-ray absorptiometry is an independent predictor of coronary artery disease extension

A. Bestetti
Primo
;
R. Bigi;C. Maioli;F. Lombardi;G. Cornalba
Ultimo
2008

Abstract

Background: Controversy prevails regarding the existence of a correlation between the severity of coronary artery disease (CAD) and the extent and distribution of obesity. Purpose: To assess the correlation between total fat, truncal fat (TF), and lean mass, obtained with dual-energy X-ray absorptiometry (DEXA) and standard anthropomorphic indices (body mass index, waist circumference, waist-to-hip ratio) and to verify whether DEXA indices can predict the extent and severity of CAD. Materials and methods: Fifty-eight patients (19 females) consecutively referred for coronary angiography underwent physical examination and DEXA assessment of body composition. Results: Of the 58 patients enrolled, 22 were overweight and 13 were obese. Significant CAD was found in 39 (67%) patients. DEXA-derived total mass and fat mass enabled us to distinguish overweight from obese patients (P < 0.005), whereas just TF mass correlated with the number of diseased vessels after adjusting for body mass index, sex, age, and smoking habit (odds ratio, 8.68; 95% confidence interval: 1.02-74.10). Conclusion: TF determined by DEXA is independently related with CAD extension.
Coronary artery disease; Dual-energy X-ray absorptiometry; Truncal fat
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Settore MED/36 - Diagnostica per Immagini e Radioterapia
ago-2008
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/44662
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