Omics techniques have been widely applied to veterinary science, although mostly on farm animal productions and infectious diseases. In canine oncology, on the contrary, the use of omics methodologies is still far behind. This review presents the most recent achievement in the application of postgenomic techniques, such as transcriptomics, proteomics, and metabolomics, to canine cancer research. The protocols to recover material suitable for omics analyses from formalin-fixed, paraffin-embedded tissues are presented, and omics applications for biomarker discovery and their potential for cancer diagnostics in veterinary medicine are highlighted.

Application of post-genomic techniques in dog cancer research / F. Ceciliani, P. Roccabianca, C. Giudice, C. Lecchi. - In: MOLECULAR BIOSYSTEMS. - ISSN 1742-2051. - 12:9(2016 Aug 16), pp. 2665-2679. [10.1039/c6mb00227g]

Application of post-genomic techniques in dog cancer research

F. Ceciliani;P. Roccabianca;C. Giudice;C. Lecchi
2016

Abstract

Omics techniques have been widely applied to veterinary science, although mostly on farm animal productions and infectious diseases. In canine oncology, on the contrary, the use of omics methodologies is still far behind. This review presents the most recent achievement in the application of postgenomic techniques, such as transcriptomics, proteomics, and metabolomics, to canine cancer research. The protocols to recover material suitable for omics analyses from formalin-fixed, paraffin-embedded tissues are presented, and omics applications for biomarker discovery and their potential for cancer diagnostics in veterinary medicine are highlighted.
Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria
16-ago-2016
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/421979
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