The neuropeptide Y (NPY) family of peptides, in addition to its many physiological actions, has also been involved in the modulation of tumor progression, with specific reference to endocrine-related cancers such as neuroendocrine tumors, breast and prostate cancers. These have been found either to express NPY receptors, or to secrete NPY-related peptides, or both. The study of the role of the NPY family of peptides in the biology of endocrine-related tumors, specifically concerning cell proliferation, angiogenesis, invasion and metastatization, may help to clarify some aspects of tumor pathophysiology, as well as to indicate novel diagnostic markers and therapeutical approaches.
Role of neuropeptide Y and its receptors in the progression of endocrine-related cancer / M. Ruscica, E. Dozio, M. Motta, P. Magni. - In: PEPTIDES. - ISSN 0196-9781. - 28:2(2007 Feb), pp. 426-434. ((Intervento presentato al 8. convegno International NPY Meeting tenutosi a St Petersburg nel 2006.
Role of neuropeptide Y and its receptors in the progression of endocrine-related cancer
M. RuscicaPrimo
;E. DozioSecondo
;M. MottaPenultimo
;P. Magni
2007
Abstract
The neuropeptide Y (NPY) family of peptides, in addition to its many physiological actions, has also been involved in the modulation of tumor progression, with specific reference to endocrine-related cancers such as neuroendocrine tumors, breast and prostate cancers. These have been found either to express NPY receptors, or to secrete NPY-related peptides, or both. The study of the role of the NPY family of peptides in the biology of endocrine-related tumors, specifically concerning cell proliferation, angiogenesis, invasion and metastatization, may help to clarify some aspects of tumor pathophysiology, as well as to indicate novel diagnostic markers and therapeutical approaches.File | Dimensione | Formato | |
---|---|---|---|
PEP66997.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
523.06 kB
Formato
Adobe PDF
|
523.06 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.