The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.

Systemic features of immune recognition in the gut / B. Swiatczak, M. Rescigno, I. Cohen. - In: MICROBES AND INFECTION. - ISSN 1286-4579. - 13:12-13(2011 Nov), pp. 983-991.

Systemic features of immune recognition in the gut

M. Rescigno
Secondo
;
2011

Abstract

The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.
Immune recognition; Systems immunology; Pathogen; Pathogen-associated molecular pattern
Settore BIO/13 - Biologia Applicata
nov-2011
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/297113
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