The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrapsupported (.0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages.

Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa / A. Piralla, C. Daleno, A. Girello, S. Esposito, F. Baldanti. - In: JOURNAL OF GENERAL VIROLOGY. - ISSN 0022-1317. - 96:Pt 6(2015 Jun), pp. 1374-1379. [10.1099/vir.0.000088]

Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa

S. Esposito
Penultimo
;
2015

Abstract

The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrapsupported (.0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages.
community-acquired pneumonia; respiratory-tract infection; maximum-likeihood; genomic analysis; recombination; children; phylogenies; rhinovirus; sequence; viruses
Settore MED/38 - Pediatria Generale e Specialistica
giu-2015
Article (author)
File in questo prodotto:
File Dimensione Formato  
1374_vir000088.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 746.48 kB
Formato Adobe PDF
746.48 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/295355
Citazioni
  • ???jsp.display-item.citation.pmc??? 5
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 9
social impact