BACKGROUND: Achieving clear margins with adequate resection volumes is one of the principal goals of breast-conserving surgery. The aim of our study was to compare preoperative localization using 2 different clips, radiopaque or sonographically visible, to reach this goal. METHODS: We reviewed 209 consecutive nonpalpable breast cancers that were treated with lumpectomy: 59 with radiopaque and 150 with sonographically visible clip positioned during biopsy procedure. In the former case, preoperative localization was performed with mammography and in the latter by ultrasonography. RESULTS: Clear margins were achieved in 80.4% of patients: 57.6% in the first and 89.3% in the second group (P < .0001; odds ratio, 7.6; 95% confidence interval, 3.4 to 17.2). By using sonographically visible clips, the re-excision rate has decreased from 42.4% to 10.7%, (P < .0001), and resections resulted smaller with average calculated resection ratio of 3.54 vs 5.08 (P - .03). CONCLUSIONS: Preoperative localization using a sonographically visible clip allows a more tailored breast-conserving surgery and reduces the re-excision rate.
Localization of nonpalpable breast lesions with sonographically visible clip: optimizing tailored resection and clear margins / F. Corsi, L. Sorrentino, A. Sartani, D. Bossi, R. Amadori, M. Nebuloni, M. Truffi, M. Bonzini, D. Foschi. - In: THE AMERICAN JOURNAL OF SURGERY. - ISSN 0002-9610. - 209:6(2015), pp. 950-958. [10.1016/j.amjsurg.2014.07.010]
Localization of nonpalpable breast lesions with sonographically visible clip: optimizing tailored resection and clear margins
F. Corsi
;L. SorrentinoSecondo
;M. Nebuloni;M. Truffi;M. Bonzini;D. FoschiUltimo
2015
Abstract
BACKGROUND: Achieving clear margins with adequate resection volumes is one of the principal goals of breast-conserving surgery. The aim of our study was to compare preoperative localization using 2 different clips, radiopaque or sonographically visible, to reach this goal. METHODS: We reviewed 209 consecutive nonpalpable breast cancers that were treated with lumpectomy: 59 with radiopaque and 150 with sonographically visible clip positioned during biopsy procedure. In the former case, preoperative localization was performed with mammography and in the latter by ultrasonography. RESULTS: Clear margins were achieved in 80.4% of patients: 57.6% in the first and 89.3% in the second group (P < .0001; odds ratio, 7.6; 95% confidence interval, 3.4 to 17.2). By using sonographically visible clips, the re-excision rate has decreased from 42.4% to 10.7%, (P < .0001), and resections resulted smaller with average calculated resection ratio of 3.54 vs 5.08 (P - .03). CONCLUSIONS: Preoperative localization using a sonographically visible clip allows a more tailored breast-conserving surgery and reduces the re-excision rate.File | Dimensione | Formato | |
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