Since different clinical outcomes of periodontal bilaminar surgeries using the palate or the maxillary tuberosity as connective tissue (CT) donor sites have been observed, tissues grafted with CT from the palate or the tuberosity 1 year after surgical procedures for ridge augmentation were compared with nongrafted tissues by using morphologic and molecular methods. Collagen content and matrix metalloproteinases 1 and 2 expression were similar in tissues and cultured fibroblasts from the palate and tuberosity, although with interindividual differences. In contrast, differences in collagen cross-linking and maturation in the tuberosity fibroblasts were observed, suggesting a possible role in determining hyperplastic responses in some patients.
Human palatal and tuberosity mucosa as donor sites for ridge augmentation / C. Dellavia, G. Ricci, L. Pettinari, C. Allievi, F. Grizzi, N. Gagliano. - In: THE INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY. - ISSN 0198-7569. - 34:2(2014), pp. 178-186. [10.11607/prd.1929]
Human palatal and tuberosity mucosa as donor sites for ridge augmentation
C. Dellavia
Primo
;L. Pettinari;C. Allievi;N. GaglianoUltimo
2014
Abstract
Since different clinical outcomes of periodontal bilaminar surgeries using the palate or the maxillary tuberosity as connective tissue (CT) donor sites have been observed, tissues grafted with CT from the palate or the tuberosity 1 year after surgical procedures for ridge augmentation were compared with nongrafted tissues by using morphologic and molecular methods. Collagen content and matrix metalloproteinases 1 and 2 expression were similar in tissues and cultured fibroblasts from the palate and tuberosity, although with interindividual differences. In contrast, differences in collagen cross-linking and maturation in the tuberosity fibroblasts were observed, suggesting a possible role in determining hyperplastic responses in some patients.File | Dimensione | Formato | |
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