Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to assess 10 patients with MCD of unknown cause. Four of the 10 patients were positive for CMV.

Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment / C. Zucca, S. Binda, R. Borgatti, F. Triulzi, L. Radice, C. Buttè, P.E. Barkhaus, M. Barbi. - In: NEUROLOGY. - ISSN 0028-3878. - 61:5(2003 Sep 09), pp. 710-712.

Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment

S. Binda
Secondo
;
F. Triulzi;M. Barbi
Ultimo
2003

Abstract

Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to assess 10 patients with MCD of unknown cause. Four of the 10 patients were positive for CMV.
Cerebral Cortex ; Child, Preschool ; Cytomegalovirus Infections ; Female ; Humans ; Infant ; Magnetic Resonance Imaging ; Male ; Nervous System Malformations ; Retrospective Studies
Settore MED/42 - Igiene Generale e Applicata
9-set-2003
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/235393
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