Two studies in this issue of Cell Stem Cell highlight context-dependent roles for MSCs in controlling tumor growth. Lee et al. (2012) show that preactivated MSCs have antitumor effects upon adoptive transfer in vivo, and Ren et al. (2012) show that tumor-resident MSCs can promote tumor growth by influencing macrophages.
MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois / A. Mantovani. - In: CELL STEM CELL. - ISSN 1934-5909. - 11:6(2012 Dec 07), pp. 730-732. [10.1016/j.stem.2012.11.016]
MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois
A. MantovaniPrimo
2012
Abstract
Two studies in this issue of Cell Stem Cell highlight context-dependent roles for MSCs in controlling tumor growth. Lee et al. (2012) show that preactivated MSCs have antitumor effects upon adoptive transfer in vivo, and Ren et al. (2012) show that tumor-resident MSCs can promote tumor growth by influencing macrophages.
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