The mechanically adaptable connective tissue of echinoderms (Mutable Collagenous Tissue—MCT), which can undergo drastic nervously-mediated changes in mechanical properties, represents a promising model for biomaterial design and biomedical applications. MCT could be a source of, or an inspiration for, new composite materials whose molecular interactions and structural conformation can be changed in response to external stimuli. MCT is composed mostly of collagen fibrils, comparable to those of mammals, plus a variety of other components, including other fibrillar structures, proteoglycans and glycoproteins. This contribution presents the preliminary results of a detailed analysis of MCT components in the sea-urchin Paracentrotus lividus, focusing on biochemical characterization of the fibrils and biomolecular analysis of the presumptive glycoproteins involved. The final aims will be to confirm the presence and the role of these glycoproteins in echinoids and to manipulate simpler components in order to produce a composite with mutable mechanical properties.

New insights into the mutable collagenous tissue of Paracentrotus lividus : preliminary results / S. Tricarico, A. Barbaglio, N. Burlini, L. Del Giacco, A. Ghilardi, M. Sugni, C. Di Benedetto, F. Bonasoro, I.C. Wilkie, M.D. Candia. - In: ZOOSYMPOSIA. - ISSN 1178-9913. - 7:1(2012 Dec 12), pp. 279-285. ((Intervento presentato al 7. convegno European Echinoderm Conference tenutosi a Göttingen nel 2010.

New insights into the mutable collagenous tissue of Paracentrotus lividus : preliminary results

S. Tricarico
Primo
;
A. Barbaglio
Secondo
;
N. Burlini;L. Del Giacco;A. Ghilardi;M. Sugni;C. Di Benedetto;F. Bonasoro;M.D. Candia
Ultimo
2012

Abstract

The mechanically adaptable connective tissue of echinoderms (Mutable Collagenous Tissue—MCT), which can undergo drastic nervously-mediated changes in mechanical properties, represents a promising model for biomaterial design and biomedical applications. MCT could be a source of, or an inspiration for, new composite materials whose molecular interactions and structural conformation can be changed in response to external stimuli. MCT is composed mostly of collagen fibrils, comparable to those of mammals, plus a variety of other components, including other fibrillar structures, proteoglycans and glycoproteins. This contribution presents the preliminary results of a detailed analysis of MCT components in the sea-urchin Paracentrotus lividus, focusing on biochemical characterization of the fibrils and biomolecular analysis of the presumptive glycoproteins involved. The final aims will be to confirm the presence and the role of these glycoproteins in echinoids and to manipulate simpler components in order to produce a composite with mutable mechanical properties.
Mutable Collagenous Tissue ; Echinodermata ; Echinoidea ; glycoproteins ; mechanical properties
Settore BIO/05 - Zoologia
12-dic-2012
http://www.mapress.com/zoosymposia/content/2012/v7/index.htm
Article (author)
File in questo prodotto:
File Dimensione Formato  
v007p279-286.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 3.66 MB
Formato Adobe PDF
3.66 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/214389
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact