Mouth-to-cecum transit and serum bile acid profile after ingestion of a lactulose-labeled liquid meal (440 kcal) were measured in eight patients with gallstones and a radiologically functioning gallbladder before and three to five months after cholecystectomy and in 15 controls. In the patients mouth-to-cecum transit was longer after the operation, 87.5 +/- 18.5 (mean +/- SEM) min vs 57.5 +/- 9.7 min (P less than 0.05). Mouth-to-cecum transit times before and after the operation were not different from controls (58.0 +/- 6.7 min). Serum bile acid AUCs were similar (P = NS) in patients and controls, while total bile acid and cholylglycine fasting concentrations were higher after cholecystectomy (P less than 0.05 and P less than 0.01 respectively). Cholecystectomy prolongs mouth-to-cecum transit of a liquid meal

Effect of cholecystectomy on mounth-to-caecum transit of a liquid meal / R. Penagini, R.C. Spiller, J.J. Misiewicz, P.G. Frost, D.B.A. Silk. - In: DIGESTIVE DISEASES AND SCIENCES. - ISSN 0163-2116. - 33:1(1988), pp. 19-22.

Effect of cholecystectomy on mounth-to-caecum transit of a liquid meal

R. Penagini
Primo
;
1988

Abstract

Mouth-to-cecum transit and serum bile acid profile after ingestion of a lactulose-labeled liquid meal (440 kcal) were measured in eight patients with gallstones and a radiologically functioning gallbladder before and three to five months after cholecystectomy and in 15 controls. In the patients mouth-to-cecum transit was longer after the operation, 87.5 +/- 18.5 (mean +/- SEM) min vs 57.5 +/- 9.7 min (P less than 0.05). Mouth-to-cecum transit times before and after the operation were not different from controls (58.0 +/- 6.7 min). Serum bile acid AUCs were similar (P = NS) in patients and controls, while total bile acid and cholylglycine fasting concentrations were higher after cholecystectomy (P less than 0.05 and P less than 0.01 respectively). Cholecystectomy prolongs mouth-to-cecum transit of a liquid meal
bile acids; breath test; cholecystectomy; gastrointestinal motility
Settore MED/12 - Gastroenterologia
1988
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/213022
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