Dendritic cells (DC) are professional APC patrolling tissues to sense danger signals and to acitivate specific immune responses. In addition they play a role in inflammation and tissue repair. Here we show that oxygen availability is necessary to promote full monocyte-derived DC differentiation and maturation.
Divergent effects of hypoxia on dendritic cell functions / A. Mancino, MG. Totaro, T. Schioppa, P. Larghi, F. Pasqualini, M. Nebuloni, IH. Chen, S. Sozzani, JM. Austyn, A. Mantovani, A. Sica. ((Intervento presentato al convegno International Congress on cytokines in immune regulation and disease tenutosi a Firenze nel 2008.
Divergent effects of hypoxia on dendritic cell functions
M. Nebuloni;A. MantovaniPenultimo
;
2008
Abstract
Dendritic cells (DC) are professional APC patrolling tissues to sense danger signals and to acitivate specific immune responses. In addition they play a role in inflammation and tissue repair. Here we show that oxygen availability is necessary to promote full monocyte-derived DC differentiation and maturation.
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