To evaluate the potential role of HCV infection in an epidemic of hepatitis B and nAnB among intravenous drug abusers (IVDA) we have retrospectively analyze by an Elisa test (Ortho) their frozen sera. A high circulation of HCV had occurred among IVDA and in most instances HCV infection was experienced earlier than, or contemporary with, HBV infection. HCV infection was associated with a high rate of chronicity among patients with nAnB hepatitis and with persistence of liver damage in patients with hepatitis B after HBsAg clearance. Neither coinfection nor previous infection with HCV did apparently interfere with the clearance of HBsAg during acute hepatitis B.
High circulation of hepatitis C virus in drug abusers with acute viral hepatitis :epidemiological and clinical implications / F. Bortolotti, A. Tagger, C. Crivellaro, M.L. Ribero, D. Cavalletto, A. Alberti. ((Intervento presentato al convegno The 1990 International Symposium on Viral Hepatitis and Liver Disease: Contemporary Issues and Future Prospects tenutosi a Houston , Texas nel 1990 , April 4-8.
High circulation of hepatitis C virus in drug abusers with acute viral hepatitis :epidemiological and clinical implications
A. TaggerSecondo
;M.L. Ribero;
1990
Abstract
To evaluate the potential role of HCV infection in an epidemic of hepatitis B and nAnB among intravenous drug abusers (IVDA) we have retrospectively analyze by an Elisa test (Ortho) their frozen sera. A high circulation of HCV had occurred among IVDA and in most instances HCV infection was experienced earlier than, or contemporary with, HBV infection. HCV infection was associated with a high rate of chronicity among patients with nAnB hepatitis and with persistence of liver damage in patients with hepatitis B after HBsAg clearance. Neither coinfection nor previous infection with HCV did apparently interfere with the clearance of HBsAg during acute hepatitis B.
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