The HLA-SD phenotype distributions of hebephrenic and paranoid schizophrenics, and of the two groups combined, in an Italian population and in a combined group from the Swedish population have been analyzed statistically. There is a significantly decreased frequency of HLA-A10 in all of these. Theae are some preliminary indications of an increased frequency (a positive association) for some of the other antigens of the HLA-SD series, but there is insufficient data at present for evaluating the significance of these findings. Differences between hebephrenic and paranoid schizophrenics have been detected.
HLA-SD antigens and schizophrenia: statistical and genetical considerations / E. Smeraldi, L. Bellodi, R. Scorza-Smeraldi, G. Fabio, E. Sacchetti. - In: TISSUE ANTIGENS. - ISSN 0001-2815. - 8:3(1976 Sep), pp. 191-6-196.
HLA-SD antigens and schizophrenia: statistical and genetical considerations
R. Scorza-Smeraldi;G. FabioPenultimo
;
1976
Abstract
The HLA-SD phenotype distributions of hebephrenic and paranoid schizophrenics, and of the two groups combined, in an Italian population and in a combined group from the Swedish population have been analyzed statistically. There is a significantly decreased frequency of HLA-A10 in all of these. Theae are some preliminary indications of an increased frequency (a positive association) for some of the other antigens of the HLA-SD series, but there is insufficient data at present for evaluating the significance of these findings. Differences between hebephrenic and paranoid schizophrenics have been detected.
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