A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate.
Analysis of a Theoretical Model Based on Similarity for Studying RNA Base Pairings / P. Di Gennaro, G.G. Sello, M. Termini. - In: JOURNAL OF THEORETICAL BIOLOGY. - ISSN 0022-5193. - 181:4(1996 Aug 21), pp. 359-371.
Analysis of a Theoretical Model Based on Similarity for Studying RNA Base Pairings
G.G. SelloSecondo
;
1996
Abstract
A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate.
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