We measured systemic to pulmonary bronchial blood flow [Q̇br(s-p)] during total cardiopulmonary bypass in 15 patients with mitral stenosis and elevated pulmonary venous pressure (group A, mean pulmonary wedge pressure = 22.2±5.4 mm Hg, mean±SD) and in 15 patients with coronary artery diseases and normal pulmonary venous pressure (group B). Q̇br(s-p) is the volume of blood accumulating in the left side of the heart in the absence of pulmonary and coronary flows. This blood was vented through a cannula introduced into the left atrium and measured. Q̇br(s-p) was 76.3±13.9 ml/min (2.18±0.37 percent of extracorporeal circulation pump flow) and 22.3±2.1 (0.63±0.15) in group A and B, respectively (p<0.01). During total cardiopulmonary bypass, pulmonary venous pressure is approximately atmospheric pressure, and no differences in systemic blood pressure, extracorporeal circulation pump flow, and airways pressure were observed between group A and B. Therefore, vascular resistance through the bronchial vessels draining into the pulmonary circulation is reduced in patients with mitral stenosis and elevated pulmonary venous pressure.

Systemic to pulmonary bronchial blood flow in mitral stenosis / P.G. Agostoni, M. Agrifoglio, V. Arena, E. Doria, A. Sala, G. Susini. - In: CHEST. - ISSN 0012-3692. - 99:3(1991), pp. 642-645.

Systemic to pulmonary bronchial blood flow in mitral stenosis

P.G. Agostoni;M. Agrifoglio;V. Arena;
1991

Abstract

We measured systemic to pulmonary bronchial blood flow [Q̇br(s-p)] during total cardiopulmonary bypass in 15 patients with mitral stenosis and elevated pulmonary venous pressure (group A, mean pulmonary wedge pressure = 22.2±5.4 mm Hg, mean±SD) and in 15 patients with coronary artery diseases and normal pulmonary venous pressure (group B). Q̇br(s-p) is the volume of blood accumulating in the left side of the heart in the absence of pulmonary and coronary flows. This blood was vented through a cannula introduced into the left atrium and measured. Q̇br(s-p) was 76.3±13.9 ml/min (2.18±0.37 percent of extracorporeal circulation pump flow) and 22.3±2.1 (0.63±0.15) in group A and B, respectively (p<0.01). During total cardiopulmonary bypass, pulmonary venous pressure is approximately atmospheric pressure, and no differences in systemic blood pressure, extracorporeal circulation pump flow, and airways pressure were observed between group A and B. Therefore, vascular resistance through the bronchial vessels draining into the pulmonary circulation is reduced in patients with mitral stenosis and elevated pulmonary venous pressure.
Circulation
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Settore MED/23 - Chirurgia Cardiaca
1991
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/179666
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