We measured systemic to pulmonary bronchial blood flow [Qbr(s-p)] during total cardiopulmonary bypass in 15 patients with mitral stenosis and elevated pulmonary venous pressure (group A, mean pulmonary wedge pressure = 22.2 +/- 5.4 mm Hg, mean +/- SD) and in 15 patients with coronary artery diseases and normal pulmonary venous pressure (group B). Qbr(s-p) is the volume of blood accumulating in the left side of the heart in the absence of pulmonary and coronary flows. This blood was vented through a cannula introduced into the left atrium and measured. Qbr(s-p) was 76.3 +/- 13.9 ml/min (2.18 +/- 0.37 percent of extracorporeal circulation pump flow) and 22.3 +/- 2.1 (0.63 +/- 0.15) in group A and B, respectively (p less than 0.01). During total cardiopulmonary bypass, pulmonary venous pressure is approximately atmospheric pressure, and no differences in systemic blood pressure, extracorporeal circulation pump flow, and airways pressure were observed between group A and B. Therefore, vascular resistance through the bronchial vessels draining into the pulmonary circulation is reduced in patients with mitral stenosis and elevated pulmonary venous pressure.
|Titolo:||Systemic to pulmonary bronchial blood flow in mitral stenosis|
|Parole Chiave:||Blood Circulation; Cardiac Output; Humans; Mitral Valve Stenosis; Aged; Regional Blood Flow; Pulmonary Circulation; Coronary Disease; Venous Pressure; Body Temperature; Bronchi; Cardiopulmonary Bypass; Adult; Heart Valve Prosthesis; Mitral Valve; Middle Aged; Pulmonary Wedge Pressure; Female; Male|
|Settore Scientifico Disciplinare:||Settore MED/11 - Malattie dell'Apparato Cardiovascolare|
|Data di pubblicazione:||mar-1991|
|Digital Object Identifier (DOI):||10.1378/chest.99.3.642|
|Appare nelle tipologie:||01 - Articolo su periodico|