Respiratory gases, acid-base balance, and lactate and hemoglobin concentrations were measured in 14 fetal blood samples between 17 and 21 weeks of gestation. The samples were obtained at the time of fetoscopy performed for prenatal diagnosis. Results have been compared with two reference groups: (a) 4 patients in whom fetal cord blood sampling was performed at 32-36 weeks of gestation, and (b) 10 patients at the time of elective cesarean section, 35-39 weeks. PO2 and oxygen saturations were significantly higher and hemoglobin concentration lower in the mid-gestation fetus. Acid-base balance was not significantly different. There was a significant correlation between maternal and fetal hemoglobin concentrations. The oxygen affinity of fetal blood was not significantly different from that described for term fetuses with a oxygen saturation of less than 90%.

Respiratory gases, acid-base balance and lactate concentrations of the midterm human fetus / P. Bozzetti, M. Buscaglia, I. Cetin, A. M. Marconi, U. Nicolini, G. Pardi, E. L. Makowski, F. C. Battaglia. - In: BIOLOGY OF THE NEONATE. - ISSN 0006-3126. - 52:4(1987), pp. 188-197.

Respiratory gases, acid-base balance and lactate concentrations of the midterm human fetus

I. Cetin;A. M. Marconi;G. Pardi;
1987

Abstract

Respiratory gases, acid-base balance, and lactate and hemoglobin concentrations were measured in 14 fetal blood samples between 17 and 21 weeks of gestation. The samples were obtained at the time of fetoscopy performed for prenatal diagnosis. Results have been compared with two reference groups: (a) 4 patients in whom fetal cord blood sampling was performed at 32-36 weeks of gestation, and (b) 10 patients at the time of elective cesarean section, 35-39 weeks. PO2 and oxygen saturations were significantly higher and hemoglobin concentration lower in the mid-gestation fetus. Acid-base balance was not significantly different. There was a significant correlation between maternal and fetal hemoglobin concentrations. The oxygen affinity of fetal blood was not significantly different from that described for term fetuses with a oxygen saturation of less than 90%.
Animals; Humans; Sheep; Gestational Age; Pregnancy; Acid-Base Equilibrium; Fetal Hemoglobin; Oxygen; Lactates; Fetal Blood; Blood Gas Analysis; Fetoscopy; Female
Settore MED/40 - Ginecologia e Ostetricia
1987
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/189718
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