Morbidly obese patients, during anesthesia and paralysis, experience more severe impairment of respiratory mechanics and gas exchange than normal subjects. The authors hypothesized that positive end-expiratory pressure (PEEP) induces different responses in normal subjects (n = 9; body mass index < 25 kg/m2) versus obese patients (n = 9; body mass index > 40 kg/m2).
Positive end-expiratory pressure improves respiratory function in obese but not in normal subjects during anesthesia and paralysis / P. Pelosi, I. Ravagnan, G. Giurati, M. Panigada, N. Bottino, S. Tredici, G. Eccher, L. Gattinoni. - In: ANESTHESIOLOGY. - ISSN 0003-3022. - 91:5(1999 Nov), pp. 1221-31-1231. [10.1097/00000542-199911000-00011]
Positive end-expiratory pressure improves respiratory function in obese but not in normal subjects during anesthesia and paralysis
L. GattinoniUltimo
1999
Abstract
Morbidly obese patients, during anesthesia and paralysis, experience more severe impairment of respiratory mechanics and gas exchange than normal subjects. The authors hypothesized that positive end-expiratory pressure (PEEP) induces different responses in normal subjects (n = 9; body mass index < 25 kg/m2) versus obese patients (n = 9; body mass index > 40 kg/m2).
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