Brush cytology was used as a diagnostic aid in 85 cats affected with chronic intranasal disease. Fifty-three of these cases, sampled over a five-year period, were included in this study, while the other cases were excluded due to poor cellularity of the cytological samples (nine cases) or a lack of histological or follow-up data (23 cases). Thirty-six brush samples were classified by cytology as inflammatory. Subsequent histological examination revealed a false negative diagnosis of neoplasia in six cats, two of which had malignant tumours (one adenocarcinoma and one lymphoma), the remaining four having benign tumours (two adenomas and two osteochondromas). Seventeen samples were classified by brush cytology as neoplastic. This was confirmed in 16 of these cases by histology or follow-up (nine epithelial malignant tumours, six lymphomas and one osteosarcoma). In the remaining case, a false positive diagnosis of lymphoma was made. The procedure had an overall 86.8 per cent (46/53) agreement between the diagnosis of inflammatory conditions versus neoplasia, with a sensitivity of 72.7 per cent, a specificity of 96.8 per cent, a predictive value of a positive test of 94.1 per cent and a predictive value of a negative test of 83.3 per cent.

Brush cytology in the diagnosis of chronic intranasal disease in cat / M. Caniatti, P. Roccabianca, G. Ghisleni, C. Mortellaro, S. Romussi, G. Mandelli. ((Intervento presentato al 15. convegno 15th Congress of the European Society of Veterinary Pathology tenutosi a Alghero nel 1997.

Brush cytology in the diagnosis of chronic intranasal disease in cat

M. Caniatti
Primo
;
P. Roccabianca
Secondo
;
C. Mortellaro;S. Romussi
Penultimo
;
G. Mandelli
Ultimo
1997

Abstract

Brush cytology was used as a diagnostic aid in 85 cats affected with chronic intranasal disease. Fifty-three of these cases, sampled over a five-year period, were included in this study, while the other cases were excluded due to poor cellularity of the cytological samples (nine cases) or a lack of histological or follow-up data (23 cases). Thirty-six brush samples were classified by cytology as inflammatory. Subsequent histological examination revealed a false negative diagnosis of neoplasia in six cats, two of which had malignant tumours (one adenocarcinoma and one lymphoma), the remaining four having benign tumours (two adenomas and two osteochondromas). Seventeen samples were classified by brush cytology as neoplastic. This was confirmed in 16 of these cases by histology or follow-up (nine epithelial malignant tumours, six lymphomas and one osteosarcoma). In the remaining case, a false positive diagnosis of lymphoma was made. The procedure had an overall 86.8 per cent (46/53) agreement between the diagnosis of inflammatory conditions versus neoplasia, with a sensitivity of 72.7 per cent, a specificity of 96.8 per cent, a predictive value of a positive test of 94.1 per cent and a predictive value of a negative test of 83.3 per cent.
set-1997
Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria
Settore VET/09 - Clinica Chirurgica Veterinaria
European Society of Veterinary Pathology
Brush cytology in the diagnosis of chronic intranasal disease in cat / M. Caniatti, P. Roccabianca, G. Ghisleni, C. Mortellaro, S. Romussi, G. Mandelli. ((Intervento presentato al 15. convegno 15th Congress of the European Society of Veterinary Pathology tenutosi a Alghero nel 1997.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/183867
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