Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV- C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV- C/HGV and hepatitis C virus and HIV coinfection.
Outcome of mother to infant acquired GBV-C/HGV infection / G. ZUIN, B. SACCANI, S. DI GIACOMO, E. TANZI, A.R. ZANETTI, N. PRINCIPI. - In: ARCHIVES OF DISEASE IN CHILDHOOD. FETAL AND NEONATAL EDITION. - ISSN 1359-2998. - 80:1(1999), pp. F72-F73.
Outcome of mother to infant acquired GBV-C/HGV infection
E. TANZI;A.R. ZANETTIPenultimo
;N. PRINCIPIUltimo
1999
Abstract
Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV- C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV- C/HGV and hepatitis C virus and HIV coinfection.
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