The kinetics of decomposition of the sodium salt of dehydroacetic acid (DHA.Na) in presence of formaldehyde and formaldehyde donors was investigated. The possibility of preparing systems capable of providing the cosmetic preparation with increasing amounts of DHA.Na corresponding to portions interacted with formaldehyde was explored. Data relevant to matrices prepared from ethylcellulose and polyethylene by casting and moulding process, respectively, are reported and discussed. Experimental data demonstrate the possibility of preparing polymeric systems able to control in terms of rate and duration the release of DHA.Na, according to time and concentration needs of a typical cosmetic formulation.

Controlled release of dehydroacetic acid sodium salt for the stability improvement of cosmetic formulations / A. Gazzaniga, M.E. Sangalli, F. Giordano, U. Conte, A. Semenzato, A. Bettero. - In: INTERNATIONAL JOURNAL OF COSMETIC SCIENCE. - ISSN 0142-5463. - 16:3(1994), pp. 105-112. [10.1111/j.1467-2494.1994.tb00088.x]

Controlled release of dehydroacetic acid sodium salt for the stability improvement of cosmetic formulations

A. Gazzaniga
Primo
;
M.E. Sangalli
Secondo
;
1994

Abstract

The kinetics of decomposition of the sodium salt of dehydroacetic acid (DHA.Na) in presence of formaldehyde and formaldehyde donors was investigated. The possibility of preparing systems capable of providing the cosmetic preparation with increasing amounts of DHA.Na corresponding to portions interacted with formaldehyde was explored. Data relevant to matrices prepared from ethylcellulose and polyethylene by casting and moulding process, respectively, are reported and discussed. Experimental data demonstrate the possibility of preparing polymeric systems able to control in terms of rate and duration the release of DHA.Na, according to time and concentration needs of a typical cosmetic formulation.
controlled release; polymer matrices; preservative agent; preserving systems; sodium dehydroacetate degradation
Settore CHIM/09 - Farmaceutico Tecnologico Applicativo
1994
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/177465
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