A new synthetic method for the one-pot preparation of aldoximes in water was developed; the method is based on the combination of the enzymatic oxidation of primary alcohols to aldehydes using different acetic acid bacteria and in situ condensation of the aldehydes with hydroxylamine.
One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water / P. Zambelli, A. Pinto, D. Romano, E. Crotti, P. Conti, L. Tamborini, R. Villa, F. Molinari. - In: GREEN CHEMISTRY. - ISSN 1463-9262. - 14:8(2012), pp. 2158-2161.
One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water
P. ZambelliPrimo
;A. PintoSecondo
;D. Romano;E. Crotti;P. Conti;L. Tamborini;R. VillaPenultimo
;F. MolinariUltimo
2012
Abstract
A new synthetic method for the one-pot preparation of aldoximes in water was developed; the method is based on the combination of the enzymatic oxidation of primary alcohols to aldehydes using different acetic acid bacteria and in situ condensation of the aldehydes with hydroxylamine.
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